Demise of the clones

Demise of the OTA.

Background: An impediment to the rational development of novel drugs against tuberculosis (TB) is a general paucity of knowledge concerning the metabolism of Mycobacterium tuberculosis, particularly during infection. Constraint-based modeling provides a novel approach to investigating microbial metabolism but has not yet been applied to genome-scale modeling of M. tuberculosis. Results: GSMN-TB...

The Demise of eAssessment Interoperability?

This paper examines progress made in the development of formats for the exchange of questions, tests and results. It is argued that despite large investments by vendors and educational bodies the specifications have not reached a critical mass of adoption and that this is because there is insufficient demand by users, particularly in higher education where the assessment process is strictly con...

The demise of "Nutcracker Man".

M ore than 50 y since the first announcement of Zinjanthropus boisei at Olduvai Gorge (1, 2), the diet of Paranthropus boisei, as it is now known, has continued to be the focus of study and debate. In part, this is because it has such distinctive features, shared in some degree with the South African australopith, Paranthropus robustus: a dished, buttressed face, strongly developed muscle attac...

the effect of taftan pozzolan on the compressive strength of concrete in the environmental conditions of oman sea (chabahar port)

cement is an essential ingredient in the concrete buildings. for production of cement considerable amount of fossil fuel and electrical energy is consumed. on the other hand for generating one tone of portland cement, nearly one ton of carbon dioxide is released. it shows that 7 percent of the total released carbon dioxide in the world relates to the cement industry. considering ecological issu...

The King's Demise